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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTRK3
All Species:
22.73
Human Site:
T489
Identified Species:
50
UniProt:
Q16288
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16288
NP_001007157.1
839
94428
T489
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
T489
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Rhesus Macaque
Macaca mulatta
XP_001087476
839
94493
T489
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Dog
Lupus familis
XP_851384
762
85941
H458
P
Q
Y
F
R
Q
G
H
N
C
H
K
P
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6VNS1
825
92742
T489
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Rat
Rattus norvegicus
Q03351
864
97045
T489
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509236
908
101917
W582
F
L
D
F
G
G
P
W
I
S
G
Q
C
S
P
Chicken
Gallus gallus
Q91044
827
93162
T491
H
H
I
N
H
G
I
T
T
P
S
S
L
D
A
Frog
Xenopus laevis
NP_001079579
821
92293
N488
H
H
I
S
N
G
S
N
T
P
S
S
S
E
G
Zebra Danio
Brachydanio rerio
XP_697105
687
77429
H383
P
Q
Y
F
R
H
G
H
N
C
N
K
P
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
G381
D
A
G
R
G
N
L
G
N
L
S
D
H
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
99.4
87.9
N.A.
95.7
94.5
N.A.
65.1
88.6
56.5
64.4
N.A.
26.2
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
99.8
89.5
N.A.
97.3
96.1
N.A.
74.1
93.8
70
71.3
N.A.
43.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
100
53.3
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
100
73.3
6.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
64
% A
% Cys:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
10
0
64
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
19
73
19
10
0
0
10
0
0
0
10
% G
% His:
64
64
0
0
55
10
0
19
0
0
10
0
10
0
0
% H
% Ile:
0
0
64
0
0
0
55
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% K
% Leu:
0
10
0
0
0
0
10
0
0
10
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
55
10
10
0
10
28
0
10
0
0
0
0
% N
% Pro:
19
0
0
0
0
0
10
0
0
64
0
0
19
0
10
% P
% Gln:
0
19
0
0
0
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
0
0
10
73
64
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
55
64
0
0
0
0
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _